Born and raised in Odense, Denmark, Jorgensen made his home in the United States for over 45 years. Best known for his work with Atlantic Salmon flies, Poul was also an outstanding creator of "ultra-realistic flies" and superb trout flies.

During a visit to the Roscoe, New York area in 1980, Jorgensen fell in love with the Catskill waters and decided to make his home in Roscoe, in a cottage on the banks of the Willowemoc Creek. He was known as a "Fly Tyer's - Tyer" a great and enthusiastic teacher and angler, Jorgensen who became a full time professional fly tyer in 1969, authored several books and videos. "Fly tying is a school from which, one never graduates", was just one of the many quotes attributted to Poul. In 2001 Poul Jorgensen was inducted into the Catskill Fly Fishing Center's Hall of Fame, an honor he held dearly. Poul Jorgensen passed away on November 29, 2004 in the little cottage that he loved, on the banks of the waters that he loved so much.